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Spatial localization of cathepsins: Implications in immune activation and resolution during infections

Cathepsins were first described, as endolysosomal proteolytic enzymes in reference to the organelles where they degrade the bulk of endogenous and exogenous substrates in a slightly acidic environment. These substrates include pathogens internalized via endocytosis and/or marked for destruction by a...

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Detalles Bibliográficos
Autores principales: Anes, Elsa, Pires, David, Mandal, Manoj, Azevedo-Pereira, José Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382241/
https://www.ncbi.nlm.nih.gov/pubmed/35990632
http://dx.doi.org/10.3389/fimmu.2022.955407