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Spatial localization of cathepsins: Implications in immune activation and resolution during infections
Cathepsins were first described, as endolysosomal proteolytic enzymes in reference to the organelles where they degrade the bulk of endogenous and exogenous substrates in a slightly acidic environment. These substrates include pathogens internalized via endocytosis and/or marked for destruction by a...
Autores principales: | Anes, Elsa, Pires, David, Mandal, Manoj, Azevedo-Pereira, José Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382241/ https://www.ncbi.nlm.nih.gov/pubmed/35990632 http://dx.doi.org/10.3389/fimmu.2022.955407 |
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