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Co-expression network analysis of human tau-transgenic mice reveals protein modules associated with tau-induced pathologies
Abnormally accumulated tau protein aggregates are one of the hallmarks of neurodegenerative diseases, including Alzheimer’s disease (AD). In order to investigate proteomic alteration driven by tau aggregates, we implemented quantitative proteomics to analyze disease model mice expressing human MAPT(...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382322/ https://www.ncbi.nlm.nih.gov/pubmed/35992067 http://dx.doi.org/10.1016/j.isci.2022.104832 |