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Identifying novel mechanisms of abdominal aortic aneurysm via unbiased proteomics and systems biology

BACKGROUND: Abdominal aortic aneurysm (AAA), characterized by a continued expansion of the aorta, leads to rupture if not surgically repaired. Mice aid the study of disease progression and its underlying mechanisms since sequential studies of aneurysm development are not feasible in humans. The pres...

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Detalles Bibliográficos
Autores principales: Morgan, Stephanie, Lee, Lang Ho, Halu, Arda, Nicolau, Jessica S., Higashi, Hideyuki, Ha, Anna H., Wen, Jennifer R., Daugherty, Alan, Libby, Peter, Cameron, Scott J., Mix, Doran, Aikawa, Elena, Owens, A. Phillip, Singh, Sasha A., Aikawa, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382335/
https://www.ncbi.nlm.nih.gov/pubmed/35990960
http://dx.doi.org/10.3389/fcvm.2022.889994