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Molecular mechanism of CD44 homodimerization modulated by palmitoylation and membrane environments

The homodimerization of CD44 plays a key role in an intercellular-to-extracellular signal transduction and tumor progression. Acylated modification and specific membrane environments have been reported to mediate translocation and oligomerization of CD44; however, the underlying molecular mechanism...

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Detalles Bibliográficos
Autores principales: Ma, Ziyi, Shi, Sai, Ren, Meina, Pang, Chunli, Zhan, Yong, An, Hailong, Sun, Fude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382338/
https://www.ncbi.nlm.nih.gov/pubmed/35733341
http://dx.doi.org/10.1016/j.bpj.2022.06.021