Optogenetic manipulation of cyclic guanosine monophosphate to probe phosphodiesterase activities in megakaryocytes

Cyclic guanosine monophosphate (cGMP) signalling plays a fundamental role in many cell types, including platelets. cGMP has been implicated in platelet formation, but mechanistic detail about its spatio-temporal regulation in megakaryocytes (MKs) is lacking. Optogenetics is a technique which allows...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yujing, Benz, Pascal, Stehle, Daniel, Yang, Shang, Kurz, Hendrikje, Feil, Susanne, Nagel, Georg, Feil, Robert, Gao, Shiqiang, Bender, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382455/
https://www.ncbi.nlm.nih.gov/pubmed/35975649
http://dx.doi.org/10.1098/rsob.220058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382455/
https://www.ncbi.nlm.nih.gov/pubmed/35975649
http://dx.doi.org/10.1098/rsob.220058

Ejemplares similares