Monodispersed Sirolimus-Loaded PLGA Microspheres with a Controlled Degree of Drug–Polymer Phase Separation for Drug-Coated Implantable Medical Devices and Subcutaneous Injection

[Image: see text] Monodispersed sirolimus (SRL)-loaded poly(lactic-co-glycolic acid) microspheres with a diameter of 1.8, 3.8, and 8.5 μm were produced by high-throughput microfluidic step emulsification—solvent evaporation using single crystal silicon chips consisted of 540–1710 terraced microchann...

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Detalles Bibliográficos
Autores principales: Zhang, Zilin, Ekanem, Ekanem E., Nakajima, Mitsutoshi, Bolognesi, Guido, Vladisavljević, Goran T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382632/
https://www.ncbi.nlm.nih.gov/pubmed/35848106
http://dx.doi.org/10.1021/acsabm.2c00319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382632/
https://www.ncbi.nlm.nih.gov/pubmed/35848106
http://dx.doi.org/10.1021/acsabm.2c00319

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