Deficiency of the RNA-binding protein Cth2 extends yeast replicative lifespan by alleviating its repressive effects on mitochondrial function

Iron dyshomeostasis contributes to aging, but little information is available about the molecular mechanisms. Here, we provide evidence that in Saccharomyces cerevisiae, aging is associated with altered expression of genes involved in iron homeostasis. We further demonstrate that defects in the cons...

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Detalles Bibliográficos
Autores principales: Patnaik, Praveen K., Beaupere, Carine, Barlit, Hanna, Romero, Antonia María, Tsuchiya, Mitsuhiro, Muir, Michael, Martínez-Pastor, María Teresa, Puig, Sergi, Kaeberlein, Matt, Labunskyy, Vyacheslav M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382658/
https://www.ncbi.nlm.nih.gov/pubmed/35858543
http://dx.doi.org/10.1016/j.celrep.2022.111113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382658/
https://www.ncbi.nlm.nih.gov/pubmed/35858543
http://dx.doi.org/10.1016/j.celrep.2022.111113

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