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The amount of DNA combined with TP53 mutations in liquid biopsy is associated with clinical outcome of renal cancer patients treated with immunotherapy and VEGFR-TKIs

BACKGROUND: Despite the increasing number of treatment options, reliable prognostic/predictive biomarkers are still missing for patients affected by metastatic clear cell renal cell carcinoma (mccRCC). METHODS: Patients with mccRCC undergoing standard first line treatment were enrolled. Blood (12 ml...

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Detalles Bibliográficos
Autores principales: Del Re, Marzia, Crucitta, Stefania, Paolieri, Federico, Cucchiara, Federico, Verzoni, Elena, Bloise, Francesco, Ciampi, Raffaele, Mercinelli, Chiara, Capuano, Annalisa, Sportiello, Liberata, Martinetti, Antonia, Procopio, Giuseppe, Galli, Luca, Porta, Camillo, Bracarda, Sergio, Danesi, Romano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382729/
https://www.ncbi.nlm.nih.gov/pubmed/35974365
http://dx.doi.org/10.1186/s12967-022-03557-7