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Optimization of the production process for the anticancer lead compound illudin M: downstream processing

BACKGROUND: Secondary metabolites have played a key role as starting points for drug development programs due to their often unique features compared with synthetically derived molecules. However, limitations related to the discovery and supply of these molecules by biotechnological means led to the...

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Detalles Bibliográficos
Autores principales: Chaverra-Muñoz, Lillibeth, Briem, Theresa, Hüttel, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382783/
https://www.ncbi.nlm.nih.gov/pubmed/35978411
http://dx.doi.org/10.1186/s12934-022-01886-2