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MiR-942-5p targeting the IFI27 gene regulates HCT-8 cell apoptosis via a TRAIL-dependent pathway during the early phase of Cryptosporidium parvum infection

BACKGROUND: MicroRNAs (miRNAs) are involved in the regulation of both the innate and adaptive immune response to Cryptosporidium parvum infection. We previously reported that C. parvum upregulated miR‑942‑5p expression in HCT‑8 cells via TLR2/TLR4‑NF‑κB signaling. In the present study, the role of m...

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Detalles Bibliográficos
Autores principales: Xie, Fujie, Zhang, Yajun, Li, Juanfeng, Sun, Lulu, Zhang, Longxian, Qi, Meng, Zhang, Sumei, Jian, Fuchun, Li, Xiaoying, Li, Junqiang, Ning, Changsheng, Wang, Rongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382849/
https://www.ncbi.nlm.nih.gov/pubmed/35974384
http://dx.doi.org/10.1186/s13071-022-05415-3