Infigratinib Reduces Fibroblast Growth Factor 23 (FGF23) and Increases Blood Phosphate in Tumor‐Induced Osteomalacia

Tumor‐induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by ectopic production of fibroblast growth factor 23 (FGF23) by phosphaturic mesenchymal tumors (PMTs). Acting on renal tubule cells, excess FGF23 decreases phosphate reabsorption and 1,25‐dihydroxy‐vitamin D (1,25D) productio...

Descripción completa

Detalles Bibliográficos
Autores principales: Hartley, Iris R., Roszko, Kelly L., Li, Xiaobai, Pozo, Karen, Streit, Jamie, del Rivero, Jaydira, Magone, M. Teresa, Smith, Michaele R., Vold, Roo, Dambkowski, Carl L., Collins, Michael T., Gafni, Rachel I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Clinical Trial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382865/
https://www.ncbi.nlm.nih.gov/pubmed/35991529
http://dx.doi.org/10.1002/jbm4.10661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382865/
https://www.ncbi.nlm.nih.gov/pubmed/35991529
http://dx.doi.org/10.1002/jbm4.10661

Ejemplares similares