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The role of adjuvant chemotherapy in the management of acute promyelocytic leukemia differentiation syndrome

Acute Promyelocytic Leukemia (APL) is characterized by the t(15;17) chromosomal translocation resulting in a PML-RARA fusion protein. The all-trans-retinoic acid (ATRA) and Arsenic Trioxide (ATO) only regimens have demonstrated success in treating low- and intermediate-risk patients. However, induct...

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Detalles Bibliográficos
Autores principales: LaBella, Dominic, Regan, Samuel, Konig, Heiko, Egan, Daniel N., Bailey, Neil A., Mawad, Raya, Gilbert, Morgan, Pagel, John M., Pu, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9383033/
https://www.ncbi.nlm.nih.gov/pubmed/35992790
http://dx.doi.org/10.3389/fonc.2022.911745