rTg(Tau(P301L))4510 mice exhibit increased VGlut1 in hippocampal presynaptic glutamatergic vesicles and increased extracellular glutamate release

The molecular pathways that contribute to the onset of symptoms in tauopathy models, including Alzheimer’s disease (AD), are difficult to distinguish because multiple changes can happen simultaneously at different stages of disease progression. Understanding early synaptic alterations and their supp...

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Detalles Bibliográficos
Autores principales: Taipala, Erika, Pfitzer, Jeremiah C., Hellums, Morgan, Reed, Miranda N., Gramlich, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9383415/
https://www.ncbi.nlm.nih.gov/pubmed/35989711
http://dx.doi.org/10.3389/fnsyn.2022.925546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9383415/
https://www.ncbi.nlm.nih.gov/pubmed/35989711
http://dx.doi.org/10.3389/fnsyn.2022.925546

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