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rTg(Tau(P301L))4510 mice exhibit increased VGlut1 in hippocampal presynaptic glutamatergic vesicles and increased extracellular glutamate release
The molecular pathways that contribute to the onset of symptoms in tauopathy models, including Alzheimer’s disease (AD), are difficult to distinguish because multiple changes can happen simultaneously at different stages of disease progression. Understanding early synaptic alterations and their supp...
Autores principales: | Taipala, Erika, Pfitzer, Jeremiah C., Hellums, Morgan, Reed, Miranda N., Gramlich, Michael W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9383415/ https://www.ncbi.nlm.nih.gov/pubmed/35989711 http://dx.doi.org/10.3389/fnsyn.2022.925546 |
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