An N-capping asparagine–lysine–proline (NKP) motif contributes to a hybrid flexible/stable multifunctional peptide scaffold

Structural diversity drives multiple biological activities and mechanisms of action in linear peptides. Here we describe an unusual N-capping asparagine-lysine-proline (NKP) motif that confers a hybrid multifunctional scaffold to a computationally designed peptide (PaDBS1R7). PaDBS1R7 has a shorter...

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Detalles Bibliográficos
Autores principales: Cardoso, Marlon H., Chan, Lai Y., Cândido, Elizabete S., Buccini, Danieli F., Rezende, Samilla B., Torres, Marcelo D. T., Oshiro, Karen G. N., Silva, Ítala C., Gonçalves, Sónia, Lu, Timothy K., Santos, Nuno C., de la Fuente-Nunez, Cesar, Craik, David J., Franco, Octávio L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9383710/
https://www.ncbi.nlm.nih.gov/pubmed/36093022
http://dx.doi.org/10.1039/d1sc06998e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9383710/
https://www.ncbi.nlm.nih.gov/pubmed/36093022
http://dx.doi.org/10.1039/d1sc06998e

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