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A model system for antiviral siRNA therapeutics using exosome-based delivery

Emerging viral diseases, such as Ebola, SARS, MERS, and the pathogen causing COVID-19, SARS-CoV-2, present a challenge for the development of therapeutics because of strict biosafety handling procedures and rapid mutation of their genomes. To facilitate the development of an adaptable and testable t...

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Detalles Bibliográficos
Autores principales: Wallen, Margaret, Aqil, Farrukh, Kandimalla, Raghuram, Jeyabalan, Jeyaprakash, Auwardt, Supipi, Tyagi, Neha, Schultz, David J., Spencer, Wendy, Gupta, Ramesh C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9384066/
https://www.ncbi.nlm.nih.gov/pubmed/35992044
http://dx.doi.org/10.1016/j.omtn.2022.08.011