Evolutionary progression of collective mutations in Omicron sub-lineages towards efficient RBD-hACE2: Allosteric communications between and within viral and human proteins

The interaction between the Spike (S) protein of SARS-CoV-2 and the human angiotensin converting enzyme 2 (hACE2) is essential for infection, and is a target for neutralizing antibodies. Consequently, selection of mutations in the S protein is expected to be driven by the impact on the interaction w...

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Detalles Bibliográficos
Autores principales: Barozi, Victor, Edkins, Adrienne L., Tastan Bishop, Özlem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9384468/
https://www.ncbi.nlm.nih.gov/pubmed/35989699
http://dx.doi.org/10.1016/j.csbj.2022.08.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9384468/
https://www.ncbi.nlm.nih.gov/pubmed/35989699
http://dx.doi.org/10.1016/j.csbj.2022.08.015

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