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Association of ERBB2 Copy Number and Gene Coalterations With Trastuzumab Efficacy and Resistance in Human Epidermal Growth Factor Receptor 2–Positive Esophagogastric and Gastric Cancer

ERBB2 copy number (CN), measured using next-generation sequencing, is a predictive biomarker for trastuzumab efficacy in human epidermal growth factor receptor 2 (HER2)–positive advanced esophagogastric and gastric cancer (AGC). We aimed to investigate the association of ERBB2 amplification and gene...

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Detalles Bibliográficos
Autores principales: Hino, Kaori, Nishina, Tomohiro, Kajiwara, Takeshi, Bando, Hideaki, Nakamura, Maho, Kadowaki, Shigenori, Minashi, Keiko, Yuki, Satoshi, Ohta, Takashi, Hara, Hiroki, Mizukami, Takuro, Moriwaki, Toshikazu, Ohtsubo, Koushiro, Komoda, Masato, Mitani, Seiichiro, Nagashima, Fumio, Kato, Ken, Yamada, Takanobu, Hasegawa, Hiroko, Yamazaki, Kentaro, Yoshino, Takayuki, Hyodo, Ichinosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9384954/
https://www.ncbi.nlm.nih.gov/pubmed/35952320
http://dx.doi.org/10.1200/PO.22.00135