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The TPR domain of PgaA is a multifunctional scaffold that binds PNAG and modulates PgaB-dependent polymer processing

The synthesis of exopolysaccharides as biofilm matrix components by pathogens is a crucial factor for chronic infections and antibiotic resistance. Many periplasmic proteins involved in polymer processing and secretion in Gram-negative synthase dependent exopolysaccharide biosynthetic systems have b...

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Detalles Bibliográficos
Autores principales: Pfoh, Roland, Subramanian, Adithya S., Huang, Jingjing, Little, Dustin J., Forman, Adam, DiFrancesco, Benjamin R., Balouchestani-Asli, Negar, Kitova, Elena N., Klassen, John S., Pomès, Régis, Nitz, Mark, Howell, P. Lynne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9384988/
https://www.ncbi.nlm.nih.gov/pubmed/35930610
http://dx.doi.org/10.1371/journal.ppat.1010750