Metabolic analyses reveal dysregulated NAD(+) metabolism and altered mitochondrial state in ulcerative colitis

Ulcerative colitis (UC) is a complex, multifactorial disease driven by a dysregulated immune response against host commensal microbes. Despite rapid advances in our understanding of host genomics and transcriptomics, the metabolic changes in UC remain poorly understood. We thus sought to investigate...

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Detalles Bibliográficos
Autores principales: Kang, Yu Hui, Tucker, Sarah A., Quevedo, Silvia F., Inal, Aslihan, Korzenik, Joshua R., Haigis, Marcia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385040/
https://www.ncbi.nlm.nih.gov/pubmed/35976971
http://dx.doi.org/10.1371/journal.pone.0273080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385040/
https://www.ncbi.nlm.nih.gov/pubmed/35976971
http://dx.doi.org/10.1371/journal.pone.0273080

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