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Metabolic analyses reveal dysregulated NAD(+) metabolism and altered mitochondrial state in ulcerative colitis
Ulcerative colitis (UC) is a complex, multifactorial disease driven by a dysregulated immune response against host commensal microbes. Despite rapid advances in our understanding of host genomics and transcriptomics, the metabolic changes in UC remain poorly understood. We thus sought to investigate...
Autores principales: | Kang, Yu Hui, Tucker, Sarah A., Quevedo, Silvia F., Inal, Aslihan, Korzenik, Joshua R., Haigis, Marcia C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385040/ https://www.ncbi.nlm.nih.gov/pubmed/35976971 http://dx.doi.org/10.1371/journal.pone.0273080 |
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