Deletion of the Plasmodium falciparum exported protein PTP7 leads to Maurer’s clefts vesiculation, host cell remodeling defects, and loss of surface presentation of EMP1

Presentation of the variant antigen, Plasmodium falciparum erythrocyte membrane protein 1 (EMP1), at knob-like protrusions on the surface of infected red blood cells, underpins the parasite’s pathogenicity. Here we describe a protein PF3D7_0301700 (PTP7), that functions at the nexus between the inte...

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Detalles Bibliográficos
Autores principales: Carmo, Olivia M. S., Shami, Gerald J., Cox, Dezerae, Liu, Boyin, Blanch, Adam J., Tiash, Snigdha, Tilley, Leann, Dixon, Matthew W. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385048/
https://www.ncbi.nlm.nih.gov/pubmed/35930605
http://dx.doi.org/10.1371/journal.ppat.1009882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385048/
https://www.ncbi.nlm.nih.gov/pubmed/35930605
http://dx.doi.org/10.1371/journal.ppat.1009882

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