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Deletion of the Plasmodium falciparum exported protein PTP7 leads to Maurer’s clefts vesiculation, host cell remodeling defects, and loss of surface presentation of EMP1
Presentation of the variant antigen, Plasmodium falciparum erythrocyte membrane protein 1 (EMP1), at knob-like protrusions on the surface of infected red blood cells, underpins the parasite’s pathogenicity. Here we describe a protein PF3D7_0301700 (PTP7), that functions at the nexus between the inte...
Autores principales: | Carmo, Olivia M. S., Shami, Gerald J., Cox, Dezerae, Liu, Boyin, Blanch, Adam J., Tiash, Snigdha, Tilley, Leann, Dixon, Matthew W. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385048/ https://www.ncbi.nlm.nih.gov/pubmed/35930605 http://dx.doi.org/10.1371/journal.ppat.1009882 |
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