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Establishment of an enzyme-linked immunosorbent assay for mouse pancreatic polypeptide clarifies the regulatory mechanism of its secretion from pancreatic γ cells

Pancreatic polypeptide (PP), secreted from γ cells of the islets of Langerhans, is a 36 amino-acid peptide encoded by the Ppy gene. Although previous studies have reported that PP causes a decrease in appetite, the molecular mechanism that regulates PP secretion has not been fully elucidated. Lack o...

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Detalles Bibliográficos
Autores principales: Saito, Daisuke, Nakagawa, Yuko, Sato, Takashi, Fukunaka, Ayako, Pereye, Ofejiro Blessing, Maruyama, Nobuhiro, Watada, Hirotaka, Fujitani, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385059/
https://www.ncbi.nlm.nih.gov/pubmed/35976945
http://dx.doi.org/10.1371/journal.pone.0269958