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SEMgsa: topology-based pathway enrichment analysis with structural equation models

BACKGROUND: Pathway enrichment analysis is extensively used in high-throughput experimental studies to gain insight into the functional roles of pre-defined subsets of genes, proteins and metabolites. Methods that leverages information on the topology of the underlying pathways outperform simpler me...

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Detalles Bibliográficos
Autores principales: Grassi, Mario, Tarantino, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385099/
https://www.ncbi.nlm.nih.gov/pubmed/35978279
http://dx.doi.org/10.1186/s12859-022-04884-8