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SEMgsa: topology-based pathway enrichment analysis with structural equation models
BACKGROUND: Pathway enrichment analysis is extensively used in high-throughput experimental studies to gain insight into the functional roles of pre-defined subsets of genes, proteins and metabolites. Methods that leverages information on the topology of the underlying pathways outperform simpler me...
Autores principales: | Grassi, Mario, Tarantino, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385099/ https://www.ncbi.nlm.nih.gov/pubmed/35978279 http://dx.doi.org/10.1186/s12859-022-04884-8 |
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