Cargando…

Distinct impact of IgG subclass on autoantibody pathogenicity in different IgG4-mediated diseases

IgG4 is the least potent human IgG subclass for the FcγR-mediated antibody effector function. Paradoxically, IgG4 is also the dominant IgG subclass of pathogenic autoantibodies in IgG4-mediated diseases. Here, we show that the IgG subclass and Fc-FcγR interaction have a distinct impact on the pathog...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bi, Yanxia, Su, Jian, Zhou, Shengru, Zhao, Yingjie, Zhang, Yan, Zhang, Huihui, Liu, Mingdong, Zhou, Aiwu, Xu, Jianrong, Pan, Meng, Zhao, Yiming, Li, Fubin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385207/ https://www.ncbi.nlm.nih.gov/pubmed/35920621 http://dx.doi.org/10.7554/eLife.76223

Ejemplares similares

Subclasses of allergen-specific IgG: Serum IgG2 and IgG3 levels are not predicted by IgG1/IgG4 levels
por: MacGlashan, Donald, et al.
Publicado: (2021)

Factors associated with IgG levels in adults with IgG subclass deficiency
por: Barton, James C., et al.
Publicado: (2021)

Pathogenicity and Epitope Characteristics Do Not Differ in IgG Subclass-Switched Anti-Desmoglein 3 IgG1 and IgG4 Autoantibodies in Pemphigus Vulgaris
por: Lo, Agnes S., et al.
Publicado: (2016)

PPD-specific IgG and IgG subclasses in the sera of pulmonary tuberculosis patients.
por: Hwang, P. H., et al.
Publicado: (1993)

Characterization of adult patients with IgG subclass deficiency and subnormal IgG2
por: Barton, James C., et al.
Publicado: (2020)

Specific Antibody Deficiency in Adult Patients With IgG or IgG Subclass Deficiency
por: Kim, Joo-Hee, et al.
Publicado: (2020)

Immunofluorescence Staining for IgG Subclass: Cause for Discrepancy in the Detection of IgG1
por: Kudose, Satoru, et al.
Publicado: (2023)

Subclass distribution of IgG autoantibodies to deiminated fibrinogen in rheumatoid arthritis
por: Chapuy-Regaud, S, et al.
Publicado: (2003)

Serum IgG Subclasses in Autoimmune Diseases
por: Zhang, Haoze, et al.
Publicado: (2015)

IgG subclass deposition in diabetic nephropathy
por: Tang, Xuanli, et al.
Publicado: (2022)

Reference ranges for serum immunoglobulin (IgG, IgA, and IgM) and IgG subclass levels in healthy children
por: BAYRAM, Rumeysa Olcay, et al.
Publicado: (2019)

The N-Glycosylation of Mouse Immunoglobulin G (IgG)-Fragment Crystallizable Differs Between IgG Subclasses and Strains
por: de Haan, Noortje, et al.
Publicado: (2017)

Definition of IgG Subclass-Specific Glycopatterns in Idiopathic Membranous Nephropathy: Aberrant IgG Glycoforms in Blood
por: Chinello, Clizia, et al.
Publicado: (2022)

The relevance of the IgG subclass of autoantibodies for blister induction in autoimmune bullous skin diseases
por: Sitaru, Cassian, et al.
Publicado: (2007)

Fc-Mediated Functions of Porcine IgG Subclasses
por: Paudyal, Basudev, et al.
Publicado: (2022)

Impact of IgG subclass on monoclonal antibody developability
por: Cain, Paul, et al.
Publicado: (2023)

CSF cytokine profile in MOG-IgG+ neurological disease is similar to AQP4-IgG+ NMOSD but distinct from MS: a cross-sectional study and potential therapeutic implications
por: Kaneko, Kimihiko, et al.
Publicado: (2018)

Tolerability and Efficacy of s.c. IgG Self-Treatment in ME/CFS Patients with IgG/IgG Subclass Deficiency: A Proof-of-Concept Study
por: Scheibenbogen, Carmen, et al.
Publicado: (2021)

Analysis of differences between total IgG and sum of the IgG subclasses in children with suspected immunodeficiency – indication of determinants
por: Pasternak, Gerard, et al.
Publicado: (2018)

Neurological disorders-associated anti-glycosphingolipid IgG-antibodies display differentially restricted IgG subclass distribution
por: Lardone, Ricardo D., et al.
Publicado: (2020)

Effectiveness of Strongyloides Recombinant IgG Immunoreactive Antigen in Detecting IgG and IgG4 Subclass Antibodies for Diagnosis of Human Strongyloidiasis Using Rapid Immunochromatographic Tests
por: Boonroumkaew, Patcharaporn, et al.
Publicado: (2020)

β(1) Adrenergic Receptor Autoantibodies and IgG Subclasses: Current Status and Unsolved Issues
por: Kawai, Akane, et al.
Publicado: (2023)

Immunoglobulin G passive transfer from mothers to infants: total IgG, IgG subclasses and specific antipneumococcal IgG in 6-week Malawian infants exposed or unexposed to HIV
por: Baroncelli, Silvia, et al.
Publicado: (2022)

Virally induced modulation of murine IgG antibody subclasses
Publicado: (1988)

IgG Subclasses and Allotypes: From Structure to Effector Functions
por: Vidarsson, Gestur, et al.
Publicado: (2014)

Biophysical and Functional Characterization of Rhesus Macaque IgG Subclasses
por: Boesch, Austin W., et al.
Publicado: (2016)

Antiparanodal antibodies and IgG subclasses in acute autoimmune neuropathy
por: Appeltshauser, Luise, et al.
Publicado: (2020)

IgG subclasses in cryoglobulins: link to composition and clinical manifestations
por: Kolopp-Sarda, Marie N., et al.
Publicado: (2020)

Influence of the bispecific antibody IgG subclass on T cell redirection
por: Kapelski, Stephanie, et al.
Publicado: (2019)

Impact of IgG subclass on molecular properties of monoclonal antibodies
por: Tang, Yu, et al.
Publicado: (2021)

The Potential Diagnostic Biomarkers for the IgG Subclass in Coal Workers' Pneumoconiosis
por: Li, Zhao-Guo, et al.
Publicado: (2023)

Human cytomegalovirus antagonizes activation of Fcγ receptors by distinct and synergizing modes of IgG manipulation
por: Kolb, Philipp, et al.
Publicado: (2021)

Lymphocyte membrane IgG and secreted IgG are structurally and allotypically distinct
Publicado: (1980)

IgG4-related disease presenting as a solitary paratesticular fibrous pseudotumor
por: Garber, Martin E., et al.
Publicado: (2021)

The antiinflammatory activity of IgG: the intravenous IgG paradox
por: Nimmerjahn, Falk, et al.
Publicado: (2007)

Subclass restriction of murine antibodies. III. Antigens that stimulate IgG3 in mice stimulate IgG2c in rats
Publicado: (1980)

Serum IgG4 levels outperform IgG4/IgG RNA ratio in differential diagnosis of IgG4-related disease
por: Schulte, Lucas A., et al.
Publicado: (2020)

Peri-ureteric mass an unusual case of immunoglobin G4-related disease (IgG4-RD)
por: Williams, Isabella S.C., et al.
Publicado: (2021)

Clinical significance of the detection of serum IgG4 and IgG4/IgG ratio in patients with thyroid-associated ophthalmopathy
por: Zhao, JianGuo, et al.
Publicado: (2023)

Effects of adjuvants on IgG subclasses elicited by virus-like Particles
por: Visciano, Maria Luisa, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_qn32bh7k9tbj4vgh3afa9bgptm