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High expression of Sterol-O-Acyl transferase 1 (SOAT1), an enzyme involved in cholesterol metabolism, is associated with earlier biochemical recurrence in high risk prostate cancer

BACKGROUND: Prostate cancer (PCa) is the most frequent cancer in men. The prognosis of PCa is heterogeneous with many clinically indolent tumors and rare highly aggressive cases. Reliable tissue markers of prognosis are lacking. Active cholesteryl ester synthesis has been associated with prostate ca...

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Detalles Bibliográficos
Autores principales: Eckhardt, Carolin, Sbiera, Iuliu, Krebs, Markus, Sbiera, Silviu, Spahn, Martin, Kneitz, Burkhard, Joniau, Steven, Fassnacht, Martin, Kübler, Hubert, Weigand, Isabel, Kroiss, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385470/
https://www.ncbi.nlm.nih.gov/pubmed/34326474
http://dx.doi.org/10.1038/s41391-021-00431-3