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Enteric glial adenosine 2B receptor signaling mediates persistent epithelial barrier dysfunction following acute DSS colitis

Intestinal epithelial barrier function is compromised in inflammatory bowel disease and barrier dysfunction contributes to disease progression. Extracellular nucleotides/nucleosides generated in gut inflammation may regulate barrier function through actions on diverse cell types. Enteric glia modula...

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Detalles Bibliográficos
Autores principales: Grubišić, Vladimir, Bali, Vedrana, Fried, David E., Eltzschig, Holger K., Robson, Simon C., Mazei-Robison, Michelle S., Gulbransen, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385475/
https://www.ncbi.nlm.nih.gov/pubmed/35869148
http://dx.doi.org/10.1038/s41385-022-00550-7