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GTSF1 accelerates target RNA cleavage by PIWI-clade Argonaute proteins

Argonaute proteins use nucleic acid guides to find and bind specific DNA or RNA target sequences. Argonaute proteins have diverse biological functions and many retain their ancestral endoribonuclease activity, cleaving the phosphodiester bond between target nucleotides t10 and t11. In animals, the P...

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Detalles Bibliográficos
Autores principales: Arif, Amena, Bailey, Shannon, Izumi, Natsuko, Anzelon, Todd A., Ozata, Deniz M., Andersson, Cecilia, Gainetdinov, Ildar, MacRae, Ian J., Tomari, Yukihide, Zamore, Phillip D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385479/
https://www.ncbi.nlm.nih.gov/pubmed/35772669
http://dx.doi.org/10.1038/s41586-022-05009-0