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Myelin repair is fostered by the corticosteroid medrysone specifically acting on astroglial subpopulations

BACKGROUND: Multiple sclerosis is characterised by inflammation, oligodendrocyte loss and axonal demyelination and shows an additional impact on astrocytes, and their polarization. Although a certain degree of spontaneous myelin repair can be observed, disease progression, and aging impair regenerat...

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Detalles Bibliográficos
Autores principales: Silva Oliveira Junior, Markley, Schira-Heinen, Jessica, Reiche, Laura, Han, Seulki, de Amorim, Vanessa Cristina Meira, Lewen, Isabel, Gruchot, Joel, Göttle, Peter, Akkermann, Rainer, Azim, Kasum, Küry, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385547/
https://www.ncbi.nlm.nih.gov/pubmed/35952494
http://dx.doi.org/10.1016/j.ebiom.2022.104204