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Myelin repair is fostered by the corticosteroid medrysone specifically acting on astroglial subpopulations
BACKGROUND: Multiple sclerosis is characterised by inflammation, oligodendrocyte loss and axonal demyelination and shows an additional impact on astrocytes, and their polarization. Although a certain degree of spontaneous myelin repair can be observed, disease progression, and aging impair regenerat...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385547/ https://www.ncbi.nlm.nih.gov/pubmed/35952494 http://dx.doi.org/10.1016/j.ebiom.2022.104204 |