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Extracellular ATP and its derivatives provide spatiotemporal guidance for bone adaptation to wide spectrum of physical forces

ATP is a ubiquitous intracellular molecule critical for cellular bioenergetics. ATP is released in response to mechanical stimulation through vesicular release, small tears in cellular plasma membranes, or when cells are destroyed by traumatic forces. Extracellular ATP is degraded by ecto-ATPases to...

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Detalles Bibliográficos
Autores principales: Dsouza, Chrisanne, Moussa, Mahmoud S., Mikolajewicz, Nicholas, Komarova, Svetlana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385560/
https://www.ncbi.nlm.nih.gov/pubmed/35992507
http://dx.doi.org/10.1016/j.bonr.2022.101608