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Environment-Sensitive Ectodomain Shedding of Epithin/PRSS14 Increases Metastatic Potential of Breast Cancer Cells by Producing CCL2

Epithin/PRSS14 is a membrane serine protease that plays a key role in tumor progression. The protease exists on the cell surface until its ectodomain shedding, which releases most of the extracellular domain. Previously, we showed that the remaining portion on the membrane undergoes intramembrane pr...

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Detalles Bibliográficos
Autores principales: Jang, Jiyoung, Cho, Eun Hye, Cho, Youngkyung, Ganzorig, Binderya, Kim, Ki Yeon, Kim, Moon Gyo, Kim, Chungho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385564/
https://www.ncbi.nlm.nih.gov/pubmed/35950457
http://dx.doi.org/10.14348/molcells.2022.2004