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SARS-CoV-2 causes secretory diarrhea with an enterotoxin-like mechanism, which is reduced by diosmectite

BACKGROUND AND AIMS: The pathophysiology of SARS-CoV-2-associated diarrhea is unknown. Using an experimental model validated for rotavirus-induced diarrhea, we investigated the effects of SARS-CoV-2 on transepithelial ion fluxes and epithelial integrity of human intestinal cells. The effect of the a...

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Detalles Bibliográficos
Autores principales: Poeta, Marco, Cioffi, Valentina, Buccigrossi, Vittoria, Corcione, Francesco, Peltrini, Roberto, Amoresano, Angela, Magurano, Fabio, Viscardi, Maurizio, Fusco, Giovanna, Tarallo, Antonietta, Damiano, Carla, Lo Vecchio, Andrea, Bruzzese, Eugenia, Guarino, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385603/
https://www.ncbi.nlm.nih.gov/pubmed/35996551
http://dx.doi.org/10.1016/j.heliyon.2022.e10246