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Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis

Cardiovascular diseases are the leading cause of premature death and disability worldwide, with both genetic and environmental determinants. While genome-wide association studies have identified multiple genetic loci associated with cardiovascular diseases, exact genes driving these associations rem...

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Detalles Bibliográficos
Autores principales: Ruotsalainen, Sanni E., Surakka, Ida, Mars, Nina, Karjalainen, Juha, Kurki, Mitja, Kanai, Masahiro, Krebs, Kristi, Graham, Sarah, Mishra, Pashupati P., Mishra, Binisha H., Sinisalo, Juha, Palta, Priit, Lehtimäki, Terho, Raitakari, Olli, Milani, Lili, Okada, Yukinori, Palotie, Aarno, Widen, Elisabeth, Daly, Mark J., Ripatti, Samuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385630/
https://www.ncbi.nlm.nih.gov/pubmed/35978133
http://dx.doi.org/10.1038/s42003-022-03552-0