A lignan from Alnus japonica inhibits glioblastoma tumorspheres by suppression of FOXM1

Forkhead Box M1 (FOXM1) is known to regulate cell proliferation, apoptosis and tumorigenesis. The lignan, (−)-(2R,3R)-1,4-O-diferuloylsecoisolariciresinol (DFS), from Alnus japonica has shown anti-cancer effects against colon cancer cells by suppressing FOXM1. The present study hypothesized that DFS...

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Detalles Bibliográficos
Autores principales: Shim, Jin-Kyoung, Lim, Seung Hoon, Jeong, Ji Hye, Choi, Ran Joo, Oh, Yoojung, Park, Junseong, Choi, Sunghee, Hong, Junpyo, Kim, Seo Jin, Moon, Ju Hyung, Kim, Eui Hyun, Teo, Wan-Yee, Park, Bong Jin, Chang, Jong Hee, Ryu, Jae-Ha, Kang, Seok-Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385634/
https://www.ncbi.nlm.nih.gov/pubmed/35978012
http://dx.doi.org/10.1038/s41598-022-18185-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385634/
https://www.ncbi.nlm.nih.gov/pubmed/35978012
http://dx.doi.org/10.1038/s41598-022-18185-w

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