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Halogenation of tyrosine perturbs large-scale protein self-organization

Protein halogenation is a common non-enzymatic post-translational modification contributing to aging, oxidative stress-related diseases and cancer. Here, we report a genetically encodable halogenation of tyrosine residues in a reconstituted prokaryotic filamentous cell-division protein (FtsZ) as a p...

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Detalles Bibliográficos
Autores principales: Sun, Huan, Jia, Haiyang, Kendall, Olivia, Dragelj, Jovan, Kubyshkin, Vladimir, Baumann, Tobias, Mroginski, Maria-Andrea, Schwille, Petra, Budisa, Nediljko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385671/
https://www.ncbi.nlm.nih.gov/pubmed/35977922
http://dx.doi.org/10.1038/s41467-022-32535-2