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m6A RNA methylation-mediated NDUFA4 promotes cell proliferation and metabolism in gastric cancer

Gastric cancer (GC) is a malignancy with poor prognosis. NDUFA4 is reported to correlate with the progression of GC. However, its underlying mechanism in GC is unknown. Our study was to reveal the pathogenic mechanism of NDUFA4 in GC. NDUFA4 expression was explored in single-cell and bulk RNA-seq da...

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Detalles Bibliográficos
Autores principales: Xu, Weihong, Lai, Yanan, Pan, Yunqi, Tan, Meiyu, Ma, Yanyun, Sheng, Huiming, Wang, Jiucun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385701/
https://www.ncbi.nlm.nih.gov/pubmed/35977935
http://dx.doi.org/10.1038/s41419-022-05132-w