Experimental exploration of a ribozyme neutral network using evolutionary algorithm and deep learning

A neutral network connects all genotypes with equivalent phenotypes in a fitness landscape and plays an important role in the mutational robustness and evolvability of biomolecules. In contrast to earlier theoretical works, evidence of large neutral networks has been lacking in recent experimental s...

Descripción completa

Detalles Bibliográficos
Autores principales: Rotrattanadumrong, Rachapun, Yokobayashi, Yohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385714/
https://www.ncbi.nlm.nih.gov/pubmed/35977956
http://dx.doi.org/10.1038/s41467-022-32538-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385714/
https://www.ncbi.nlm.nih.gov/pubmed/35977956
http://dx.doi.org/10.1038/s41467-022-32538-z

Ejemplares similares