Hypoxia mimetics restore bone biomineralisation in hyperglycaemic environments

Diabetic patients have an increased risk of fracture and an increased occurrence of impaired fracture healing. Diabetic and hyperglycaemic conditions have been shown to impair the cellular response to hypoxia, via an inhibited hypoxia inducible factor (HIF)-1α pathway. We investigated, using an in v...

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Detalles Bibliográficos
Autores principales: Rezaei, Azadeh, Li, Yutong, Turmaine, Mark, Bertazzo, Sergio, Howard, Christopher A., Arnett, Timothy R., Shakib, Kaveh, Jell, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385857/
https://www.ncbi.nlm.nih.gov/pubmed/35977987
http://dx.doi.org/10.1038/s41598-022-18067-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385857/
https://www.ncbi.nlm.nih.gov/pubmed/35977987
http://dx.doi.org/10.1038/s41598-022-18067-1

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