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Dominant-negative p53-overexpression in skeletal muscle induces cell death and fiber atrophy in rats
The tumor suppressor p53 is thought to play a key role in the maintenance of cell size and homeostasis, but relatively little is known about its role in skeletal muscle. Based on its ability to suppress cell growth, we hypothesized that inhibiting the function of wild-type p53 through the overexpres...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385859/ https://www.ncbi.nlm.nih.gov/pubmed/35977948 http://dx.doi.org/10.1038/s41419-022-05160-6 |