What a Difference an Amino Acid Makes: An All-Atom Simulation Study of Nonameric Peptides in Inhibitory HLA-E/NKG2A/CD94 Immune Complexes

MHC class I antigen E (HLA-E), a ligand for the inhibitory NKG2A/CD94 receptor of the immune system, is responsible for evading the immune surveillance in several settings, including senescent cell accumulation and tumor persistence. The formation of this ligand-receptor interaction promotes the inh...

Descripción completa

Detalles Bibliográficos
Autores principales: Prašnikar, Eva, Perdih, Andrej, Borišek, Jure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385950/
https://www.ncbi.nlm.nih.gov/pubmed/35991867
http://dx.doi.org/10.3389/fphar.2022.925427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385950/
https://www.ncbi.nlm.nih.gov/pubmed/35991867
http://dx.doi.org/10.3389/fphar.2022.925427

Ejemplares similares