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An integrative pan cancer analysis of RET aberrations and their potential clinical implications

RET (rearranged during transfection), encoding a tyrosine kinase receptor, is a novel therapeutic target for cancers. The aberrations of RET are commonly found in cancers. Here, we profiled a comprehensive genomic landscape of RET mutations, copy number variants (CNVs), co-occurrence of RET and its...

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Detalles Bibliográficos
Autores principales: Zhou, Lei, Li, Juanni, Zhang, Xiaofang, Xu, Zhijie, Yan, Yuanliang, Hu, Kuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386015/
https://www.ncbi.nlm.nih.gov/pubmed/35978072
http://dx.doi.org/10.1038/s41598-022-17791-y