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Verteporfin ameliorates fibrotic aspects of Dupuytren’s disease nodular fibroblasts irrespective the activation state of the cells

Dupuytren’s disease is a chronic, progressive fibroproliferative condition of the hand fascia which results in digital contraction. So far, treatments do not directly interfere with the (myo)fibroblasts that are responsible for the formation of the collagen-rich cords and its contraction. Here we in...

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Detalles Bibliográficos
Autores principales: Puerta Cavanzo, Nataly, Riesmeijer, Sophie A., Holt-Kedde, Iris L., Werker, Paul M. N., Piersma, Bram, Olinga, Peter, Bank, Ruud A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386017/
https://www.ncbi.nlm.nih.gov/pubmed/35977978
http://dx.doi.org/10.1038/s41598-022-18116-9