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dock8 deficiency attenuates microglia colonization in early zebrafish larvae

Microglia are tissue-resident macrophages that carry out immune functions in the brain. The deficiency or dysfunction of microglia has been implicated in many neurodegenerative disorders. DOCK8, a member of the DOCK family, functions as a guanine nucleotide exchange factor and plays key roles in imm...

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Detalles Bibliográficos
Autores principales: Wu, Linxiu, Xue, Rongtao, Chen, Jiahao, Xu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386030/
https://www.ncbi.nlm.nih.gov/pubmed/35977943
http://dx.doi.org/10.1038/s41420-022-01155-6