Precise detection of CRISPR-Cas9 editing in hair cells in the treatment of autosomal dominant hearing loss

Gene therapy would benefit from the effective editing of targeted cells with CRISPR-Cas9 tools. However, it is difficult to precisely assess the editing performance in vivo because the tissues contain many non-targeted cells, which is one of the major barriers to clinical translation. Here, in the A...

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Detalles Bibliográficos
Autores principales: Cui, Chong, Wang, Daqi, Huang, Bowei, Wang, Fang, Chen, Yuxin, Lv, Jun, Zhang, Luping, Han, Lei, Liu, Dong, Chen, Zheng-Yi, Li, Geng-Lin, Li, Huawei, Shu, Yilai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386031/
https://www.ncbi.nlm.nih.gov/pubmed/36035752
http://dx.doi.org/10.1016/j.omtn.2022.07.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386031/
https://www.ncbi.nlm.nih.gov/pubmed/36035752
http://dx.doi.org/10.1016/j.omtn.2022.07.016

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