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Molecular mechanism of the spider toxin κ-LhTx-I acting on the bacterial voltage-gated sodium channel NaChBac
The bacterial sodium channel NaChBac is the prokaryotic prototype for the eukaryotic Na(V) and Ca(V) channels, which could be used as a relatively simple model to study their structure–function relationships. However, few modulators of NaChBac have been reported thus far, and the pharmacology of NaC...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386039/ https://www.ncbi.nlm.nih.gov/pubmed/35991876 http://dx.doi.org/10.3389/fphar.2022.924661 |