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Molecular mechanism of the spider toxin κ-LhTx-I acting on the bacterial voltage-gated sodium channel NaChBac

The bacterial sodium channel NaChBac is the prokaryotic prototype for the eukaryotic Na(V) and Ca(V) channels, which could be used as a relatively simple model to study their structure–function relationships. However, few modulators of NaChBac have been reported thus far, and the pharmacology of NaC...

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Detalles Bibliográficos
Autores principales:	Xiao, Zhen, Li, Yaqi, Zhao, Piao, Wu, Xiangyue, Luo, Guoqing, Peng, Shuijiao, Liu, Hongrong, Tang, Cheng, Liu, Zhonghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386039/ https://www.ncbi.nlm.nih.gov/pubmed/35991876 http://dx.doi.org/10.3389/fphar.2022.924661

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